Produktnummer:
185dd009f887f34e7384af5d337f955638
| Themengebiete: | estrogen action estrogen receptor growth growth factor hormone |
|---|---|
| Veröffentlichungsdatum: | 18.01.2002 |
| EAN: | 9780896039124 |
| Sprache: | Englisch |
| Seitenzahl: | 374 |
| Produktart: | Gebunden |
| Herausgeber: | Manni, Andrea Verderame, Michael |
| Verlag: | Humana Press |
| Untertitel: | Research and Clinical Applications |
Produktinformationen "Selective Estrogen Receptor Modulators"
Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.
Sie möchten lieber vor Ort einkaufen?
Sie haben Fragen zu diesem oder anderen Produkten oder möchten einfach gerne analog im Laden stöbern? Wir sind gerne für Sie da und beraten Sie auch telefonisch.
Juristische Fachbuchhandlung
Georg Blendl
Parcellistraße 5 (Maxburg)
8033 München
Montag - Freitag: 8:15 -18 Uhr
Samstags geschlossen