Mechanism of Functional Expression of the Molecular Machines
Produktnummer:
18ee6dd37c1a394ba5858437aeabc7d3cb
| Autor: | Kinoshita, Masahiro |
|---|---|
| Themengebiete: | ATP hydrolysis cycle Protein-Ligand Interactions molecular machine motor protein self assembly water entropy |
| Veröffentlichungsdatum: | 22.06.2016 |
| EAN: | 9789811014840 |
| Sprache: | Englisch |
| Seitenzahl: | 70 |
| Produktart: | Kartoniert / Broschiert |
| Verlag: | Springer Singapore |
Produktinformationen "Mechanism of Functional Expression of the Molecular Machines"
This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.
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