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Mammary Tumorigenesis and Malignant Progression

353,09 €*

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Produktnummer: 18c0676beb09934e70b512f015b9efdf97
Themengebiete: angiogenesis biology carcinogenesis carcinoma genes hormones metastasis molecular biology oncogene ovarian cancer
Veröffentlichungsdatum: 31.07.1994
EAN: 9780792326472
Sprache: Englisch
Seitenzahl: 361
Produktart: Gebunden
Herausgeber: Dickson, Robert B. Lippman, Marc E.
Verlag: Springer US
Untertitel: Advances in Cellular and Molecular Biology of Breast Cancer
Produktinformationen "Mammary Tumorigenesis and Malignant Progression"
The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer. The first three volumes were entitled Breast Cancer: Cellular and Molecular Biology, Regulatory Mechanisms in Breast Cancer, and Genes, Oncogenes, and Hormones, respectively. Throughout this series, we have tried to take a broad look at cutting-edge topics in basic science research into breast cancer. This attempt has resulted in a wide range of subject material, including rodent and human model systems, oncogenes, suppressor genes, growth factors, hormones, tumor-host interactions, and determinants of metastases. Since our last volume, research in breast cancer has continued to proceed at an explosive rate. We hope the current volume will provide the reader with some of the excitement felt by the editors and authors as we begin to understand this all-too-common disease. The first section of this book is devoted to the basic processes of proli feration, differentiation, and malignant progression of breast cancer. T.l. Anderson and W.R. Miller lead off with a detailed description of controls on proliferation in the normal human breast and in breast cancer. This chapter strongly emphasizes pathological aspects. The second chapter, by M.R. Stampfer and P. Yaswen, presents a corresponding viewpoint through a presentation of experiments with human mammary epithelial cells in culture. The second section of the book emphasizes the genetic basis for breast cancer onset and malignant progression. Chapter 3, by M.-C. King and S.

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